Medical science has been one of the most fascinating field in the industry. It has answered several questions regarding medical diseases and most importantly discovered several treatments for the many physical diseases of human. Clodronate liposome for example, are one of those remarkable discoveries which could play a great role in medicine.
Macrophages basically is the core of the immune system. Macrophage has two functions and that includes natural immune reaction and regulating non phagocytic cells. More so, these cells plays a major role in immune responses and immunity. It will automatically defends the body, through phagocytosis of different microbes and parasite.
Through phagocytosis macrophage will be able to defend the body. Phagocytosis means the ingestion of bacteria and other foreign cell in the body by the phagocytes. In addition to that, it also activates to major lymphocytes the t lymphocytes and the b ones. In short, macrophage through phagocytosis activates the immune system of both human and animals.
Autoimmune diseases for example are disease that are caused through the immune system. Such diseases are caused by the self attack of the immune system towards certain cells on the body. Normally, the immune system is triggered by the attack of macrophages to bacteria or other foreign cell inside the body.
There are several autoimmune diseases to mention a few, this includes systemic lupus erythematosus, pernicious anemia, rheumatoid arthritis and multiple sclerosis . Transplant patients on the other hand will always face the risk of their transplanted organs on being rejected. Sometimes the body identifies the newly transplanted organ's cells to be foreign, causing an extreme attack with the immune system resulting to acute or chronic rejection.
Therefore liposomes acts as a vehicle to effectively carry clodronate inside the body and towards the cells without destroying its composition. After injecting the solution, the macrophage will then automatically identifies the substance to be foreign hence engulfing it. As soon as the macrophage ingest and digest the liposome, the main component of the drug will be released intracellularly.
Afterwhich the substance will then induce apoptosis on the macrophage, or in other words death to the cell, particularly the macrophages. Experiments with such component have shown interesting outcome specifically in suppressing macrophage activity in several autoimmune diseases. Such process can also help in suppressing immune response to transplant patients and gene therapy patients.
However this time, the cell being attacked is the macrophage. To correlate it with the autoimmune diseases, damage to the macrophage effectively suppresses the immune system making it a promising therapeutic treatment to patients with autoimmune disease and to prevent rejection to people who had just undergone transplantation. Suppression of the immune system is significant towards treatment or slowing down disease progression in autoimmune diseases.
During cancer, clodronate liposome helps by improving anti tumor effects of anti tumor drugs and effectively increase plasma absorption. This phenomenon may not be able to cure the disease itself, however the disease will be properly managed by then. There's no doubt that such component holds a great relevance in medicine, especially disease treatment. Certain countries such as Australia, Canada, Italy and the United Kingdom has allowed such treatment to be used by humans.
Macrophages basically is the core of the immune system. Macrophage has two functions and that includes natural immune reaction and regulating non phagocytic cells. More so, these cells plays a major role in immune responses and immunity. It will automatically defends the body, through phagocytosis of different microbes and parasite.
Through phagocytosis macrophage will be able to defend the body. Phagocytosis means the ingestion of bacteria and other foreign cell in the body by the phagocytes. In addition to that, it also activates to major lymphocytes the t lymphocytes and the b ones. In short, macrophage through phagocytosis activates the immune system of both human and animals.
Autoimmune diseases for example are disease that are caused through the immune system. Such diseases are caused by the self attack of the immune system towards certain cells on the body. Normally, the immune system is triggered by the attack of macrophages to bacteria or other foreign cell inside the body.
There are several autoimmune diseases to mention a few, this includes systemic lupus erythematosus, pernicious anemia, rheumatoid arthritis and multiple sclerosis . Transplant patients on the other hand will always face the risk of their transplanted organs on being rejected. Sometimes the body identifies the newly transplanted organ's cells to be foreign, causing an extreme attack with the immune system resulting to acute or chronic rejection.
Therefore liposomes acts as a vehicle to effectively carry clodronate inside the body and towards the cells without destroying its composition. After injecting the solution, the macrophage will then automatically identifies the substance to be foreign hence engulfing it. As soon as the macrophage ingest and digest the liposome, the main component of the drug will be released intracellularly.
Afterwhich the substance will then induce apoptosis on the macrophage, or in other words death to the cell, particularly the macrophages. Experiments with such component have shown interesting outcome specifically in suppressing macrophage activity in several autoimmune diseases. Such process can also help in suppressing immune response to transplant patients and gene therapy patients.
However this time, the cell being attacked is the macrophage. To correlate it with the autoimmune diseases, damage to the macrophage effectively suppresses the immune system making it a promising therapeutic treatment to patients with autoimmune disease and to prevent rejection to people who had just undergone transplantation. Suppression of the immune system is significant towards treatment or slowing down disease progression in autoimmune diseases.
During cancer, clodronate liposome helps by improving anti tumor effects of anti tumor drugs and effectively increase plasma absorption. This phenomenon may not be able to cure the disease itself, however the disease will be properly managed by then. There's no doubt that such component holds a great relevance in medicine, especially disease treatment. Certain countries such as Australia, Canada, Italy and the United Kingdom has allowed such treatment to be used by humans.
About the Author:
Find clodronate liposome by touring our web pages at www.clodrosome.com today. To watch our educational videos or to learn more about the routes of administration, check out the links at http://www.clodrosome.com now.
